When you click on a desktop icon the Properties window opens. Or, when you try to enter text into a search box, nothing happens. Why? What can be done? First, run scans to make sure you are malware and virus free. We suggest doing so in Safe Mode. (At Startup, press F-8 repeatedly until a start menu appears).
Next, the mouse settings should be checked for a setting that switches the left and right click actions. Go to the control panel and verify the correct settings in the Mouse options window. If they need to be changed, do so.
More likely, however, the issue is caused by malware or a virus that changed the registry by re-registering the shell32.dll. That would need to be changed to correct all the issues. This solution assumes you are using Windows XP.
First, click on Start and then Run. Type in the box: regsvr32 /i shell32 and then click OK. (Leave a space between regsvr32 and / and also between the i and shell32). A second dialogue box will open telling you it successfully completed the task. Restart the system and try using the mouse again and then try to type in a search box online.
If successful, create a system restore point. Go to Start, All Programs, Accessories, System Tools and then System Restore. Create a Restore Point, name it and click Create. Done.