When you try to open MS Outlook, (2007, 2010 in this example), you get the message: “Business Contact Manager failed to initialize Common Language Runtime.” This most likely came about after a significant Windows update.
The cause is due to Windows failure to run .net framework. This can be corrected by opening the Control Panel, Programs and Features window. Then click the blue link to Turn Windows Features on or off. Place a check mark next to the top to options, (.net 3.5 and 4.6), and make sure the sub options are checked as well. Close and wait for the changes to take effect. Try Outlook again.